Rabbit Anti-MED4 Recombinant Antibody (CBFYM-0316) (CBMAB-M0381-FY)

Name: Rabbit Anti-MED4 Recombinant Antibody (CBFYM-0316)
SKU: CBMAB-M0381-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBFYM-0316

Application

WB, IP, IHC-P, IF

Specificity

Mouse, Rat, Human, Fruit fly

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

MED4

Introduction

This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Entrez Gene ID

Human	29079
Mouse	67381
Rat	306030

UniProt ID

Human	Q9NPJ6
Mouse	Q9CQA5
Rat	Q561Q8

Alternative Names

Mediator Complex Subunit 4; Vitamin D3 Receptor-Interacting Protein Complex 36 KDa Component; Activator-Recruited Cofactor 36 KDa Component; DRIP36; VDRIP; ARC36; Mediator Of RNA Polymerase II Transcription, Subunit 4 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription Subunit 4

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Biological Process

Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Transcription by RNA polymerase II Source: UniProtKB

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-MED4 Recombinant Antibody (CBFYM-0616) (CAT#: CBMAB-M0750-FY)

Mouse Anti-MED4 Antibody (1A6) (CAT#: CBMAB-0650-YC)

Mouse Anti-MED4 Recombinant Antibody (2B10) (CAT#: CBMAB-A5377-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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