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Rabbit Anti-MED4 Recombinant Antibody (CBFYM-0316) (CBMAB-M0381-FY)

This product is rabbit antibody that recognizes MED4. The antibody CBFYM-0316 can be used for immunoassay techniques such as: WB, IP, IHC-P, IF.
See all MED4 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human, Fruit fly
Clone
CBFYM-0316
Antibody Isotype
IgG
Application
WB, IP, IHC-P, IF

Basic Information

Specificity
Mouse, Rat, Human, Fruit fly
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MED4
Introduction
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Entrez Gene ID
Human29079
Mouse67381
Rat306030
UniProt ID
HumanQ9NPJ6
MouseQ9CQA5
RatQ561Q8
Alternative Names
Mediator Complex Subunit 4; Vitamin D3 Receptor-Interacting Protein Complex 36 KDa Component; Activator-Recruited Cofactor 36 KDa Component; DRIP36; VDRIP; ARC36; Mediator Of RNA Polymerase II Transcription, Subunit 4 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription Subunit 4
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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