Sign in or Register   Sign in or Register
  |  

Mouse Anti-MED7 Recombinant Antibody (CBFYM-0617) (CBMAB-M0751-FY)

This product is mouse antibody that recognizes MED7. The antibody CBFYM-0617 can be used for immunoassay techniques such as: ELISA, WB.
See all MED7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-0617
Antibody Isotype
IgG2b, k
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MED7
Introduction
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Entrez Gene ID
9443
UniProt ID
O43513
Alternative Names
Mediator Complex Subunit 7; Cofactor Required For Sp1 Transcriptional Activation, Subunit 9, 33kDa; RNA Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog; Cofactor Required For Sp1 Transcriptional Activation Subunit 9; Activator-Recruited Cofactor 34 KDa Component; Transcriptional Coactivator CRSP33; CRSP Complex Subunit 9
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: MGI
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Stem cell population maintenance Source: Ensembl
Transcription initiation from RNA polymerase II promoter Source: ProtInc
Cellular Location
Nucleus
PTM
Constitutively sumoylated.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-MED7 Recombinant Antibody (CBFYM-0617)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare