Mouse Anti-MKL1 Recombinant Antibody (CBYY-1131) (CBMAB-1135-YY)

Name: Mouse Anti-MKL1 Recombinant Antibody (CBYY-1131)
SKU: CBMAB-1135-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYY-1131

Application

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

MEGAKARYOBLASTIC LEUKEMIA (TRANSLOCATION) 1

Introduction

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Entrez Gene ID

57591

UniProt ID

Q969V6

Alternative Names

Megakaryoblastic Leukemia (Translocation) 1; Myocardin-Related Transcription Factor A; Megakaryocytic Acute Leukemia Protein; Megakaryoblastic Leukemia 1 Protein; Basic, SAP And Coiled-Coil Domain; MRTF-A; MAL;

Biological Process

Positive regulation of transcription via serum response element binding Source: InterPro

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-MKL1 (AA 1-347) Recombinant Antibody (CBYY-1136) (CAT#: CBMAB-1140-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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