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Mouse Anti-MKL1 (AA 1-347) Recombinant Antibody (CBYY-1136) (CBMAB-1140-YY)

This product is mouse antibody that recognizes MKL1. The antibody CBYY-1136 can be used for immunoassay techniques such as: IHC-P, WB
See all MKL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-1136
Antibody Isotype
IgG1
Application
IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-347

Target

Full Name
MEGAKARYOBLASTIC LEUKEMIA (TRANSLOCATION) 1
Introduction
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Entrez Gene ID
57591
UniProt ID
Q969V6
Alternative Names
Megakaryoblastic Leukemia (Translocation) 1; Myocardin-Related Transcription Factor A; Megakaryocytic Acute Leukemia Protein; Megakaryoblastic Leukemia 1 Protein; Basic, SAP And Coiled-Coil Domain; MRTF-A; MAL;
Biological Process
Positive regulation of transcription via serum response element binding Source: InterPro
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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