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Mouse Anti-MLXIP (AA 481-577) Recombinant Antibody (CBFYM-2316) (CBMAB-M2501-FY)

This product is mouse antibody that recognizes MLXIP. The antibody CBFYM-2316 can be used for immunoassay techniques such as: ELISA, WB.
See all MLXIP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2316
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: PSVITHTASA TLTHDAPATT FSQSQGLVIT THHPAPSAAP CGLALSPVTR PPQPRLTFVH PKPVSLTGGR PKQPHKIVPA PKPEPVSLVL KNARIAP
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 481-577

Target

Full Name
MLXIP
Introduction
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X and is involved in the regulation of genes in response to cellular glucose levels.
Entrez Gene ID
22877
UniProt ID
Q9HAP2
Alternative Names
MLX Interacting Protein; Class E Basic Helix-Loop-Helix Protein 36; Transcriptional Activator MondoA; BHLHe36; MONDOA; MIR; MLX-Interacting Protein; Mlx Interactor; KIAA0867
Function
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm
Nucleus
Mitochondrion
Mitochondrion outer membrane
Note: Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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