Mouse Anti-MOBP Recombinant Antibody (4C2) (CBMAB-A5542-LY)

The product is antibody recognizes MOBP. The antibody 4C2 immunoassay techniques such as: WB, ELISA.
See all MOBP antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

4C2

Antibody Isotype

IgG1, κ

Application

WB, ELISA

Basic Information

Immunogen

MOBP (AAH22471, 1 a.a. ~ 81 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

myelin-associated oligodendrocyte basic protein

Entrez Gene ID

4336

UniProt ID

Q13875

Alternative Names

MGC87379

Function

May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.

Biological Process

Nervous system development Source: ProtInc

Cellular Location

Other locations
perinuclear region
Note: Present in the major dense line of CNS myelin.

References

Huang, C., Wu, Z., Wang, D., Qu, Y., Zhang, J., Jiang, R., ... & Yang, C. (2023). Myelin-associated oligodendrocytic basic protein-dependent myelin repair confers the long-lasting antidepressant effect of ketamine. Molecular Psychiatry, 1-13.

Siokas, V., Aloizou, A. M., Liampas, I., Bakirtzis, C., Tsouris, Z., Sgantzos, M., ... & Dardiotis, E. (2022). Myelin‐associated oligodendrocyte basic protein rs616147 polymorphism as a risk factor for Parkinson's disease. Acta Neurologica Scandinavica, 145(2), 223-228.

Bettencourt, C., Miki, Y., Piras, I. S., de Silva, R., Foti, S. C., Talboom, J. S., ... & Holton, J. L. (2021). MOBP and HIP1 in multiple system atrophy: New α‐synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis. Neuropathology and applied neurobiology, 47(5), 640-652.

Kon, T., Tanji, K., Mori, F., Kimura, A., Kakita, A., & Wakabayashi, K. (2019). Immunoreactivity of myelin‐associated oligodendrocytic basic protein in Lewy bodies. Neuropathology, 39(4), 279-285.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MOBP (AA 1-81) Recombinant Antibody (CBFYM-2459)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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