Mouse Anti-MPO Recombinant Antibody (A1172) (CBMAB-AP4961LY)

Name: Mouse Anti-MPO Recombinant Antibody (A1172)
SKU: CBMAB-AP4961LY
Rating: 5 (1 reviews)

See all MPO antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

A1172

Application

ICC, IHC, IP, WB

Specificity

Cattle

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

Affinity purity

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Myeloperoxidase

Introduction

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

Entrez Gene ID

511206

UniProt ID

A6QPT4

Alternative Names

Myeloperoxidase; EC 1.11.1.7; EC 1.11.2.2; EC 1.11.1;

Function

MAA601Bo21

Biological Process

Aging Source: Ensembl
Defense response Source: ProtInc
Defense response to bacterium Source: GO_Central
Defense response to fungus Source: Ensembl
Hydrogen peroxide catabolic process Source: BHF-UCL
Hypochlorous acid biosynthetic process Source: Ensembl
Low-density lipoprotein particle remodeling Source: BHF-UCL
Negative regulation of apoptotic process Source: ProtInc
Removal of superoxide radicals Source: Ensembl
Respiratory burst involved in defense response Source: Ensembl
Response to food Source: Ensembl
Response to gold nanoparticle Source: Ensembl
Response to lipopolysaccharide Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to oxidative stress Source: UniProtKB
Response to yeast Source: Ensembl

Cellular Location

Lysosome

Involvement in disease

Myeloperoxidase deficiency (MPOD):
A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis.

Frangie, C., & Daher, J. (2022). Role of myeloperoxidase in inflammation and atherosclerosis. Biomedical reports, 16(6), 1-11.

Kargapolova, Y., Geißen, S., Zheng, R., Baldus, S., Winkels, H., & Adam, M. (2021). The enzymatic and non-enzymatic function of myeloperoxidase (MPO) in inflammatory communication. Antioxidants, 10(4), 562.

Chen, S., Chen, H., Du, Q., & Shen, J. (2020). Targeting myeloperoxidase (MPO) mediated oxidative stress and inflammation for reducing brain ischemia injury: Potential application of natural compounds. Frontiers in physiology, 11, 433.

Arnhold, J. (2020). The dual role of myeloperoxidase in immune response. International Journal of Molecular Sciences, 21(21), 8057.

Davies, M. J., & Hawkins, C. L. (2020). The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease. Antioxidants & Redox Signaling, 32(13), 957-981.

Ramachandra, C. J., Ja, K. M. M., Chua, J., Cong, S., Shim, W., & Hausenloy, D. J. (2020). Myeloperoxidase as a multifaceted target for cardiovascular protection. Antioxidants & redox signaling, 32(15), 1135-1149.

Chaikijurajai, T., & Tang, W. W. (2020). Myeloperoxidase: a potential therapeutic target for coronary artery disease. Expert opinion on therapeutic targets, 24(7), 695-705.

Cheng, D., Talib, J., Stanley, C. P., Rashid, I., Michaëlsson, E., Lindstedt, E. L., ... & Stocker, R. (2019). Inhibition of MPO (myeloperoxidase) attenuates endothelial dysfunction in mouse models of vascular inflammation and atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, 39(7), 1448-1457.

Ndrepepa, G. (2019). Myeloperoxidase–A bridge linking inflammation and oxidative stress with cardiovascular disease. Clinica chimica acta, 493, 36-51.

Galijasevic, S. (2019). The development of myeloperoxidase inhibitors. Bioorganic & Medicinal Chemistry Letters, 29(1), 1-7.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-MPO Recombinant Antibody (A1172)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Recombinant Mouse Anti-MPO Antibody (CBHb229) (CAT#: CBMAB-Hb792-LY)

Mouse Anti-MPO (AA 1-193) Recombinant Antibody (CBFYM-2498) (CAT#: CBMAB-M2685-FY)

Mouse Anti-MPO Recombinant Antibody (9B12G7,4D8B12,9B12D9,9C11A5) (CAT#: CBMAB-AO746LY)

Mouse Anti-MPO Recombinant Antibody (CBFYM-0110) (CAT#: CBMAB-M0126-FY)

Mouse Anti-MPO Recombinant Antibody (CBT2842) (CAT#: V2LY-0625-LY2261)

Mouse Anti-MPO Recombinant Antibody (A1171) (CAT#: CBMAB-AP12275LY)

Mouse Anti-MPO Recombinant Antibody (CBFYM-0099) (CAT#: CBMAB-M0112-FY)

Mouse Anti-MPO Recombinant Antibody (CBFYM-0464) (CAT#: CBMAB-M0586-FY)

Mouse Anti-MPO (AA 646-745) Recombinant Antibody (CBFYM-2503) (CAT#: CBMAB-M2690-FY)

Mouse Anti-MPO Monoclonal Antibody (CBFYR0613) (CAT#: CBMAB-R0613-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry