Mouse Anti-MPPE1 Recombinant Antibody (3E4) (CBMAB-A5570-LY)

Name: Mouse Anti-MPPE1 Recombinant Antibody (3E4)
SKU: CBMAB-A5570-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3E4

Application

WB, ELISA

Immunogen

MPPE1 (AAH02877.1, 34 a.a. ~ 333 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

METALLOPHOSPHOESTERASE 1

Entrez Gene ID

65258

UniProt ID

Q53F39

Function

Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.

Biological Process

Endoplasmic reticulum to Golgi vesicle-mediated transport Source: UniProtKB
GPI anchor biosynthetic process Source: UniProtKB

Cellular Location

Golgi apparatus
cis-Golgi network membrane
Other locations
Endoplasmic reticulum-Golgi intermediate compartment membrane
Note: Also localizes to endoplasmic reticulum exit site.

Reid, K. M., Spaull, R., Salian, S., Barwick, K., Meyer, E., Zhen, J., ... & Kurian, M. A. (2022). MED27, SLC6A7, and MPPE1 variants in a complex neurodevelopmental disorder with severe dystonia. Movement Disorders, 37(10), 2139-2146.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-MPPE1 (AA 34-333) Recombinant Antibody (CBFYM-2516) (CAT#: CBMAB-M2703-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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