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MPPE1

MPPE1 (Metallophosphoesterase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoric diester hydrolase activity.

Full Name

METALLOPHOSPHOESTERASE 1

Function

Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.

Biological Process

Endoplasmic reticulum to Golgi vesicle-mediated transport Source: UniProtKB
GPI anchor biosynthetic process Source: UniProtKB

Cellular Location

Golgi apparatus
cis-Golgi network membrane
Other locations
Endoplasmic reticulum-Golgi intermediate compartment membrane
Note: Also localizes to endoplasmic reticulum exit site.

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Anti-MPPE1 antibodies

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Mouse Anti-MPPE1 Recombinant Antibody (3E4) (CBMAB-A5570-LY)

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Target: MPPE1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3E4

Application*: WB, E

Mouse Anti-MPPE1 (AA 34-333) Recombinant Antibody (CBFYM-2516) (CBMAB-M2703-FY)

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Target: MPPE1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-2516

Application*: WB

Mouse Anti-MPPE1 Recombinant Antibody (CBFYM-0712) (CBMAB-M0854-FY)

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Target: MPPE1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-0712

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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