MPPE1
MPPE1 (Metallophosphoesterase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoric diester hydrolase activity.
Full Name
METALLOPHOSPHOESTERASE 1
Function
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Biological Process
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: UniProtKB
GPI anchor biosynthetic process Source: UniProtKB
GPI anchor biosynthetic process Source: UniProtKB
Cellular Location
Golgi apparatus
cis-Golgi network membrane
Other locations
Endoplasmic reticulum-Golgi intermediate compartment membrane
Note: Also localizes to endoplasmic reticulum exit site.
cis-Golgi network membrane
Other locations
Endoplasmic reticulum-Golgi intermediate compartment membrane
Note: Also localizes to endoplasmic reticulum exit site.
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Anti-MPPE1 antibodies
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Target: MPPE1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E4
Application*: WB, E
Target: MPPE1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2516
Application*: WB
Target: MPPE1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0712
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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