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Mouse Anti-MRPL44 Recombinant Antibody (CBFYM-2564) (CBMAB-M2752-FY)

This product is mouse antibody that recognizes MRPL44. The antibody CBFYM-2564 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all MRPL44 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2564
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MITOCHONDRIAL RIBOSOMAL PROTEIN L44
Introduction
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Entrez Gene ID
65080
UniProt ID
Q9H9J2
Alternative Names
Mitochondrial Ribosomal Protein L44; Mitochondrial Large Ribosomal Subunit Protein ML44; 39S Ribosomal Protein L44, Mitochondrial; MRP-L44; L44MT; EC 3.1.26.-; EC 3.1.26; COXPD16
Function
Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
Biological Process
Mitochondrial translation Source: ComplexPortal
Mitochondrial translational elongation Source: UniProtKB
RNA processing Source: InterPro
rRNA catabolic process Source: InterPro
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 16 (COXPD16):
An autosomal recessive, mitochondrial disorder characterized by hypertrophic cardiomyopathy, liver steatosis, and decreased levels of mitochondrial complexes I and IV in heart and skeletal muscle.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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