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Mouse Anti-MRPL58 Recombinant Antibody (CBYY-I0053) (CBMAB-I0135-YY)

This product is Mouse antibody that recognizes MRPL58. The antibody CBYY-I0053 can be used for immunoassay techniques such as: WB, FC, ELISA
See all MRPL58 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-I0053
Antibody Isotype
IgG1, κ
Application
WB, FC, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Mitochondrial Ribosomal Protein L58
Introduction
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
3396
UniProt ID
Q14197
Alternative Names
Mitochondrial Ribosomal Protein L58; Mitochondrial Large Ribosomal Subunit Protein ML62; Immature Colon Carcinoma Transcript 1 Protein; 39S Ribosomal Protein L58, Mitochondrial; Digestion Substraction 1; MRP-L58; ICT1;
Function
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
Biological Process
Mitochondrial translation Source: ComplexPortal
Mitochondrial translational termination Source: UniProtKB
Cellular Location
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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