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Mouse Anti-MRPS27 (AA 151-414) Recombinant Antibody (CBFYM-2581) (CBMAB-M2769-FY)

This product is mouse antibody that recognizes MRPS27. The antibody CBFYM-2581 can be used for immunoassay techniques such as: FC, IHC-P, WB.
See all MRPS27 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2581
Antibody Isotype
IgG1
Application
FC, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 151-414

Target

Full Name
Mitochondrial Ribosomal Protein S27
Introduction
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
23107
UniProt ID
Q92552
Alternative Names
Mitochondrial Ribosomal Protein S27; Mitochondrial Small Ribosomal Subunit Protein MS27; MRP-S27; S27mt; 28S Ribosomal Protein S27, Mitochondrial; Mitochondrial 28S Ribosomal Protein S27; KIAA0264
Function
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis (PubMed:22841715).

Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain (PubMed:22841715).

Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu) (PubMed:22841715).

Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:28714366).
Biological Process
Cell population proliferation Source: UniProtKB
Mitochondrial translation Source: ComplexPortal
Positive regulation of mitochondrial translation Source: UniProtKB
Cellular Location
Cytoplasm
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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