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Mouse Anti-MTMR1 (AA 39-112) Recombinant Antibody (CBFYM-2745) (CBMAB-M2938-FY)

This product is mouse antibody that recognizes MTMR1. The antibody CBFYM-2745 can be used for immunoassay techniques such as: ELISA, WB.
See all MTMR1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2745
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: SRQPSVETLD SPTGSHVEWC KQLIAATISS QISGSVTSEN VSRDYKALRD GNKLAQMEEA PLFPGESIKA IVKD
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 39-112

Target

Full Name
myotubularin related protein 1
Introduction
This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined.
Entrez Gene ID
8776
UniProt ID
Q13613
Alternative Names
Myotubularin Related Protein 1; Phosphatidylinositol-3,5-Bisphosphate 3-Phosphatase; Phosphatidylinositol-3-Phosphate Phosphatase; EC 3.1.3.48; EC 3.1.3.95; EC 3.1.3.64; EC 3.1.3
Function
Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:11733541, PubMed:27018598).

Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown by PubMed:27018598, while PubMed:11733541 find no activity with this substrate.
Biological Process
Phosphatidylinositol biosynthetic process Source: Reactome
Phosphatidylinositol dephosphorylation Source: UniProtKB
Regulation of phosphatidylinositol dephosphorylation Source: UniProtKB
Cellular Location
Cytoplasm By similarity
Plasma membrane
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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