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Mouse Anti-NCAM1 Recombinant Antibody (5B8) (CBMAB-0243-CN)

This product is a mouse antibody that recognizes NCAM1 of rat. The antibody 5B8 can be used for immunoassay techniques such as: ELISA.
See all NCAM1 antibodies

Summary

Host Animal
Mouse
Specificity
Rat, Mouse
Clone
5B8
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Specificity
Rat, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neural Cell Adhesion Molecule 1
Introduction
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. This gene has 4 transcripts (splice variants), 107 orthologues, 8 paralogues, is a member of 1 Ensembl protein family and is associated with 14 phenotypes.
Entrez Gene ID
Mouse17967
Rat24586
UniProt ID
MouseP13595
RatP13596
Alternative Names
Cd56; Ncam; N-CAM; NCAMC; NCAM-1; NCAM-C; N-CAM-1
Function
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

(Microbial infection) Acts as a receptor for rabies virus.

(Microbial infection) Acts as a receptor for Zika virus.
Biological Process
Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Cellular Location
Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted
Topology
Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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