Mouse Anti-NCAM1 Recombinant Antibody (CBT3638) (V2LY-0625-LY1446)

Name: Mouse Anti-NCAM1 Recombinant Antibody (CBT3638)
SKU: V2LY-0625-LY1446
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-NCAM1 Recombinant Antibody (CBT3638) (V2LY-0625-LY1446) in ELISA

Mouse Anti-NCAM1 Recombinant Antibody (CBT3638) (V2LY-0625-LY1446) in WB

Mouse Anti-NCAM1 Recombinant Antibody (CBT3638) (V2LY-0625-LY1446) in FC

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBT3638

Antibody Isotype

IgG2a

Application

WB, FC

Basic Information

Immunogen

Purified recombinant fragment of human NCAM1 (AA: extra(568-708)) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Neural Cell Adhesion Molecule 1

Entrez Gene ID

4684

UniProt ID

P13591

Alternative Names

Neural Cell Adhesion Molecule 1; NCAM; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; CD56;

Function

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

(Microbial infection) Acts as a receptor for rabies virus.

(Microbial infection) Acts as a receptor for Zika virus.

Biological Process

Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL

Cellular Location

Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted

Topology

Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858

More Infomation

References

Kim, W., Watanabe, H., Lomoio, S., & Tesco, G. (2021). Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. Journal of Biological Chemistry, 296.

Caza, T. N., Hassen, S. I., Kuperman, M., Sharma, S. G., Dvanajscak, Z., Arthur, J., ... & Larsen, C. P. (2021). Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kidney international, 100(1), 171-181.

Vukojevic, V., Mastrandreas, P., Arnold, A., Peter, F., Kolassa, I. T., Wilker, S., ... & Stetak, A. (2020). Evolutionary conserved role of neural cell adhesion molecule-1 in memory. Translational psychiatry, 10(1), 217.

Jesudas, B. R., Nandeesha, H., Menon, V., & Allimuthu, P. (2020). Relationship of elevated neural cell adhesion molecule 1 with interleukin-10 and disease severity in bipolar disorder. Asian Journal of Psychiatry, 47, 101849.

Kim, Y. H., Kim, Y. H., Shin, Y. K., Jo, Y. R., Park, D. K., Song, M. Y., ... & Park, H. T. (2019). p75 and neural cell adhesion molecule 1 can identify pathologic Schwann cells in peripheral neuropathies. Annals of Clinical and Translational Neurology, 6(7), 1292-1301.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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