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Mouse Anti-NFRKB Recombinant Antibody (CBWJN-0397) (CBMAB-N0337-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-0397
Antibody Isotype
IgG1
Application
Dot, ICC, IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nuclear factor related to kappaB binding protein
Introduction
Binds to the DNA consensus sequence 5-GGGGAATCTCC-3.
Entrez Gene ID
4798
UniProt ID
Q6P4R8
Alternative Names
Nuclear Factor Related To KappaB Binding Protein; INO80 Complex Subunit G; DNA-Binding Protein R Kappa B; INO80G; Nuclear Factor Related To Kappa B Binding Protein; Nuclear Factor Related To Kappa-B-Binding Protein; DNA-Binding Protein R Kappa-B;
Function
Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex.
Biological Process
Chromatin remodelingManual Assertion Based On ExperimentIDA:ComplexPortal
DNA recombinationIEA:UniProtKB-KW
DNA repairIEA:UniProtKB-KW
Nucleosome mobilizationManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of cell cycleManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of chromosome organizationManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of DNA replicationManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of DNA strand elongationManual Assertion Based On ExperimentIMP:ComplexPortal
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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