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Mouse Anti-NGRN Recombinant Antibody (2634C2a) (CBMAB-D2140-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Neugrin, Neurite Outgrowth Associated (NGRN). The antibody can be used for immunoassay techniques, such as Dot, WB.
See all NGRN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2634C2a
Antibody Isotype
IgG2b
Application
Dot, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neugrin, Neurite Outgrowth Associated
Introduction
NGRN has ubiquitous expression in brain (RPKM 111.2), prostate (RPKM 60.9) and 25 other tissues.
Entrez Gene ID
51335
UniProt ID
Q9NPE2
Alternative Names
DSC92
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Biological Process
Mitochondrial ribosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Neuron differentiation1 PublicationNAS:UniProtKB
Positive regulation of mitochondrial translationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Secreted
Mitochondrion membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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