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NGRN

May be involved in neuronal differentiation.

Full Name

Neugrin, Neurite Outgrowth Associated

Function

Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

Biological Process

Mitochondrial ribosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Neuron differentiation1 PublicationNAS:UniProtKB
Positive regulation of mitochondrial translationManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Nucleus
Secreted
Mitochondrion membrane

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Anti-NGRN antibodies

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Mouse Anti-NGRN Recombinant Antibody (CBWJN-0538) (CBMAB-N2415-WJ)

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Target: NGRN

Host: Mouse

Specificity: Human

Clone: CBWJN-0538

Application*: WB

Mouse Anti-NGRN Recombinant Antibody (CBWJN-0316) (CBMAB-N2414-WJ)

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Target: NGRN

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBWJN-0316

Application*: DB, IC, IF, WB

Mouse Anti-NGRN Recombinant Antibody (2634C2a) (CBMAB-D2140-YC)

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Target: NGRN

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2634C2a

Application*: DB, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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