NGRN

May be involved in neuronal differentiation.

Full Name

Neugrin, Neurite Outgrowth Associated

Function

Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

Biological Process

Mitochondrial ribosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Neuron differentiation1 PublicationNAS:UniProtKB
Positive regulation of mitochondrial translationManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Nucleus
Secreted
Mitochondrion membrane

Anti-NGRN antibodies

Mouse Anti-NGRN Recombinant Antibody (CBWJN-0538) (CBMAB-N2415-WJ)

Datasheet

SDS

Target: NGRN

Host: Mouse

Specificity: Human

Clone: CBWJN-0538

Application*: WB

Mouse Anti-NGRN Recombinant Antibody (CBWJN-0316) (CBMAB-N2414-WJ)

Datasheet

SDS

Target: NGRN

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBWJN-0316

Application*: DB, IC, IF, WB

Mouse Anti-NGRN Recombinant Antibody (2634C2a) (CBMAB-D2140-YC)

Datasheet

SDS

Target: NGRN

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2634C2a

Application*: DB, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)