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Mouse Anti-NME6 Recombinant Antibody (2A10) (CBMAB-N2796-WJ)

This product is a Mouse antibody that recognizes NME6. The antibody 2A10 can be used for immunoassay techniques such as: ELISA, IHC-P, WB.
See all NME6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2A10
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
Introduction
Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]
Entrez Gene ID
10201
UniProt ID
O75414
Alternative Names
NME/NM23 Nucleoside Diphosphate Kinase 6; Non-Metastatic Cells 6, Protein Expressed In (Nucleoside-Diphosphate Kinase); Inhibitor Of P53-Induced Apoptosis-Alpha; NDP Kinase 6; IPIA-ALPHA; EC 2.7.4.6; NM23-H6; NDK 6; Nucleoside Diphosphate Kinase 6;
Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Biological Process
Apoptotic processIEA:UniProtKB-KW
CTP biosynthetic processIEA:InterPro
GTP biosynthetic processIEA:InterPro
Negative regulation of cell growthManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of mitotic nuclear divisionManual Assertion Based On ExperimentIDA:UniProtKB
UTP biosynthetic processIEA:InterPro
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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