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Mouse Anti-NPEPPS Recombinant Antibody (CBWJN-0541) (CBMAB-N3121-WJ)

This product is a Mouse antibody that recognizes NPEPPS. The antibody CBWJN-0541 can be used for immunoassay techniques such as: Dot, ICC, WB.
See all NPEPPS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-0541
Antibody Isotype
IgG2a
Application
Dot, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
AMINOPEPTIDASE PUROMYCIN SENSITIVE
Introduction
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Aminopeptidase Puromycin Sensitive; Puromycin-Sensitive Aminopeptidase; Cytosol Alanyl Aminopeptidase; Metalloproteinase MP100; AAP-S; PSA;
Function
Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
Biological Process
Cellular response to hypoxiaManual Assertion Based On ExperimentIDA:UniProtKB
Peptide catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of protein targeting to mitochondrionManual Assertion Based On ExperimentHMP:ParkinsonsUK-UCL
Protein polyubiquitinationTAS:Reactome
ProteolysisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cytosol
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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