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Mouse Anti-NT5C Recombinant Antibody (3C1) (CBMAB-N3675-WJ)

This product is a Mouse antibody that recognizes NT5C. The antibody 3C1 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all NT5C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3C1
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
5', 3'-Nucleotidase, Cytosolic
Introduction
This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
Entrez Gene ID
UniProt ID
Alternative Names
5', 3'-Nucleotidase, Cytosolic; 5, 3-Nucleotidase, Cytosolic; 5 Nucleotidase, Deoxy (Pyrimidine), Cytosolic Type C; Uridine 5-Prime Monophosphate Hydrolase 2; Cytosolic 5,3-Pyrimidine Nucleotidase; Deoxy-5-Nucleotidase 1; UMPH2; DNT-1; DNT1; 5(3)-Deoxyribonucleotidase, Cytosolic Type;
Function
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Biological Process
Allantoin metabolic processIEA:Ensembl
dCMP catabolic processIEA:Ensembl
DephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
dGMP catabolic processIEA:Ensembl
dTMP catabolic processIEA:Ensembl
dUMP catabolic processIEA:Ensembl
IMP catabolic processIEA:Ensembl
Pyrimidine deoxyribonucleotide catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
UMP catabolic processIEA:Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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