Mouse Anti-NT5C Recombinant Antibody (3C1) (CBMAB-N3675-WJ)

Name: Mouse Anti-NT5C Recombinant Antibody (3C1)
SKU: CBMAB-N3675-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3C1

Application

ELISA, IF, IHC, WB

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

5', 3'-Nucleotidase, Cytosolic

Introduction

This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

Entrez Gene ID

30833

UniProt ID

Q8TCD5

Alternative Names

5', 3'-Nucleotidase, Cytosolic; 5, 3-Nucleotidase, Cytosolic; 5 Nucleotidase, Deoxy (Pyrimidine), Cytosolic Type C; Uridine 5-Prime Monophosphate Hydrolase 2; Cytosolic 5,3-Pyrimidine Nucleotidase; Deoxy-5-Nucleotidase 1; UMPH2; DNT-1; DNT1; 5(3)-Deoxyribonucleotidase, Cytosolic Type;

Function

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.

Biological Process

Allantoin metabolic processIEA:Ensembl
dCMP catabolic processIEA:Ensembl
DephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
dGMP catabolic processIEA:Ensembl
dTMP catabolic processIEA:Ensembl
dUMP catabolic processIEA:Ensembl
IMP catabolic processIEA:Ensembl
Pyrimidine deoxyribonucleotide catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
UMP catabolic processIEA:Ensembl

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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