Rabbit Anti-NUDT19 Recombinant Antibody (CBWJN-1600) (CBMAB-N3891-WJ)

Name: Rabbit Anti-NUDT19 Recombinant Antibody (CBWJN-1600)
SKU: CBMAB-N3891-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBWJN-1600

Application

WB, IHC-P, ICC

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Nudix Hydrolase 19

Introduction

Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).

Entrez Gene ID

390916

UniProt ID

A8MXV4

Alternative Names

Nudix Hydrolase 19; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 19; Nudix Motif 19; Nucleoside Diphosphate-Linked Moiety X Motif 19, Mitochondrial; Nucleoside Diphosphate-Linked Moiety X Motif 19; CTC-379B2.4; EC 3.6.1.-; EC 3.6.1; RP2;

Function

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).
Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).
Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity).
Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).

Biological Process

Butyryl-CoA catabolic processISS:UniProtKB
Coenzyme A catabolic processISS:UniProtKB
Fatty acid catabolic processTAS:Reactome
Malonyl-CoA catabolic processISS:UniProtKB
Medium-chain fatty-acyl-CoA catabolic processISS:UniProtKB
Propionyl-CoA metabolic processISS:UniProtKB
Succinyl-CoA catabolic processISS:UniProtKB

Cellular Location

Peroxisome

Görigk, S., Ouwens, D. M., Kuhn, T., Altenhofen, D., Binsch, C., Damen, M., ... & Al-Hasani, H. (2022). Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 1867(6), 159153.

King, R. D., Vickers, S., King, J., & Leonardi, R. (2022). Elucidating the role of NUDT19 in renal lipid metabolism. The FASEB Journal, 36.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-NUDT19 Recombinant Antibody (CBWJN-1599) (CAT#: CBMAB-N3890-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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