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Mouse Anti-NUP58 Recombinant Antibody (3G11) (CBMAB-A6194-LY)

The product is antibody recognizes NUPL1. The antibody 3G11 immunoassay techniques such as: WB, ELISA.
See all NUP58 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G11
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
NUPL1 (NP_054808.1, 323 a.a. ~ 422 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Nucleoporin 58
Introduction
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
KIAA0410; PRO2463
Function
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Biological Process
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transport1 PublicationIC:ComplexPortal
Protein transportIEA:UniProtKB-KW
Regulation of protein import into nucleusIEA:Ensembl
Cellular Location
Nucleus, nuclear pore complex
Nucleus membrane
Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter.
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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