• Home
  • NUTF2
  • Mouse Anti-NUTF2 Recombinant Antibody (4F5)

Mouse Anti-NUTF2 Recombinant Antibody (4F5) (CBMAB-N4046-WJ)

See all NUTF2 antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
4F5
Application
ELISA, ICC, IF, IP, Neut, WB
Specificity
Hamster, Human, Mouse, Rat, Frog
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
15mM sodium azide
Concentration
2.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Nuclear Transport Factor 2
Introduction
This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]
Entrez Gene ID
Human10204
Mouse68051
Rat291981
Hamster100753217
Frog496540
UniProt ID
HumanP61970
MouseP61971
RatP61972
HamsterG3HKX2
FrogQ5XGB6
Alternative Names
Nuclear Transport Factor 2; Placental Protein 15; NTF-2; NTF2; PP15;
Function
Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.
Biological Process
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transportManual Assertion Based On ExperimentIBA:GO_Central
Protein export from nucleusManual Assertion Based On ExperimentIDA:BHF-UCL
Protein import into nucleusManual Assertion Based On ExperimentIDA:UniProtKB
Protein localization to nuclear poreISS:UniProtKB
Cellular Location
Cytoplasm, cytosol
Nucleus outer membrane
Nucleus, nuclear pore complex
Nucleus inner membrane
Nucleus, nucleoplasm
At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci.

Yates III, J., Gomes, F., Durbin, K., Schauer, K., Nwachukwu, J., Russo, R., ... & Nettles, K. (2023). Native top-down proteomics reveals EGFR–ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth. Research Square.

Li, P., Wen, X., Zhang, X., Wang, F., Zhang, D., & Shang, H. (2022). NUTF2 as a Prognostic Indicator and Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma. Genetic Testing and Molecular Biomarkers, 26(12), 553-563.

Zhang, R., & Gao, Y. (2021). Identification of NUTF2 as a candidate diagnostic and prognostic biomarker associated with immune infiltration in head and neck squamous cell carcinoma. OncoTargets and therapy, 5455-5467.

Du, Q., Liu, J., Tian, D., Zhang, X., Zhu, J., Qiu, W., & Wu, J. (2020). Long noncoding RNA LINC00173 promotes NUTF2 expression through sponging miR-765 and facilitates tumorigenesis in glioma. Cancer Management and Research, 7211-7217.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-NUTF2 Recombinant Antibody (4F5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-NUTF2 Recombinant Antibody (4H7F9) (CAT#: CBMAB-N4047-WJ)

Mouse Anti-NUTF2 Recombinant Antibody (5E8) (CAT#: CBMAB-N4045-WJ)

Mouse Anti-NUTF2 Recombinant Antibody (CF316) (CAT#: CBMAB-FT195LY)

Mouse Anti-NUTF2 Recombinant Antibody (J.206.1) (CAT#: CBMAB-N4049-WJ)

Mouse Anti-NUTF2 Recombinant Antibody (5A3) (CAT#: CBMAB-N3709-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry