NUTF2

This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]
Full Name
Nuclear Transport Factor 2
Function
Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.
Biological Process
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transportManual Assertion Based On ExperimentIBA:GO_Central
Protein export from nucleusManual Assertion Based On ExperimentIDA:BHF-UCL
Protein import into nucleusManual Assertion Based On ExperimentIDA:UniProtKB
Protein localization to nuclear poreISS:UniProtKB
Cellular Location
Cytoplasm, cytosol
Nucleus outer membrane
Nucleus, nuclear pore complex
Nucleus inner membrane
Nucleus, nucleoplasm
At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci.
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Anti-NUTF2 antibodies

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Mouse Anti-NUTF2 Recombinant Antibody (CF316) (CBMAB-FT195LY)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF316
Application*: ELISA, WB, IF, IHC
Datasheet SDS

Mouse Anti-NUTF2 Recombinant Antibody (J.206.1) (CBMAB-N4049-WJ)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: J.206.1
Application*: IC, IF, WB
Datasheet SDS

Mouse Anti-NUTF2 Recombinant Antibody (4H7F9) (CBMAB-N4047-WJ)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4H7F9
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-NUTF2 Recombinant Antibody (4F5) (CBMAB-N4046-WJ)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Hamster, Human, Mouse, Rat, Frog
Clone: 4F5
Application*: E, IC, IF, IP, N, WB
Datasheet SDS

Mouse Anti-NUTF2 Recombinant Antibody (5E8) (CBMAB-N4045-WJ)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Frog
Clone: 5E8
Application*: WB, IF
Datasheet SDS

Mouse Anti-NUTF2 Recombinant Antibody (5A3) (CBMAB-N3709-WJ)

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Target: NUTF2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat, Monkey
Clone: 5A3
Application*: WB, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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