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Mouse Anti-Paip2b Recombinant Antibody (E-9) (CBMAB-P0688-YC)

Provided herein is a Mouse monoclonal antibody against Mouse Poly(A) Binding Protein Interacting Protein 2B. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all Paip2b antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
E-9
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Poly(A) Binding Protein Interacting Protein 2B
Introduction
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1, a translational stimulator, and PAIP2A and PAIP2B, translational inhibitors.
Entrez Gene ID
400961
UniProt ID
Q9ULR5
Alternative Names
Poly(A) Binding Protein Interacting Protein 2B; PABP-Interacting Protein 2B; PAIP-2B; Polyadenylate-Binding Protein-Interacting Protein 2B; Poly(A)-Binding Protein-Interacting Protein 2B; KIAA1155;
Function
Inhibits translation of capped and polyadenylated mRNAs by displacing PABPC1 from the poly(A) tail.
Biological Process
Negative regulation of translationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of translational initiationManual Assertion Based On ExperimentIDA:HGNC-UCL
Cellular Location
Cytoplasm
PTM
Ubiquitinated in vitro.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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