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Mouse Anti-PAK1IP1 Recombinant Antibody (CBYC-P144) (CBMAB-P0693-YC)

Provided herein is a Mouse monoclonal antibody against Human PAK1 Interacting Protein 1. The antibody can be used for immunoassay techniques, such as WB.
See all PAK1IP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
CBYC-P144
Antibody Isotype
IgM
Application
WB

Basic Information

Specificity
Human, Rat
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PAK1 Interacting Protein 1
Introduction
PAK1IP1 has ubiquitous expression in prostate (RPKM 23.6), appendix (RPKM 6.7) and 24 other tissues.
Entrez Gene ID
Human55003
Rat361232
UniProt ID
HumanQ9NWT1
RatQ32PZ0
Alternative Names
PAK1 Interacting Protein 1; WD Repeat-Containing Protein 84; PAK/PLC-Interacting Protein 1; WDR84; HPIP1; PIP1;
Function
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868).
Biological Process
Cell population proliferationIEA:Ensembl
Negative regulation of signal transductionIEA:UniProtKB-KW
Regulation of signal transduction by p53 class mediatorManual Assertion Based On ExperimentIMP:UniProtKB
Ribosomal large subunit biogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Roof of mouth developmentIEA:Ensembl
Cellular Location
Nucleus, nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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