Mouse Anti-PARD3B Recombinant Antibody (8D7) (CBMAB-P0772-YC)

Name: Mouse Anti-PARD3B Recombinant Antibody (8D7)
SKU: CBMAB-P0772-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

8D7

Application

ELISA

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid in PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Par-3 Family Cell Polarity Regulator Beta

Introduction

PARD3B has ubiquitous expression in kidney (RPKM 1.4), fat (RPKM 1.3) and 24 other tissues.

Entrez Gene ID

117583

UniProt ID

Q8TEW8

Alternative Names

Par-3 Family Cell Polarity Regulator Beta; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 19 Protein; Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 19; Partitioning Defective 3-Like Protein; PAR3-L Protein; ALS2CR19; PAR3B; PAR3L;

Function

Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.

Biological Process

Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell cycleIEA:UniProtKB-KW
Cell divisionIEA:UniProtKB-KW
Establishment of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Establishment of centrosome localizationManual Assertion Based On ExperimentIBA:GO_Central
Establishment or maintenance of epithelial cell apical/basal polarityManual Assertion Based On ExperimentIBA:GO_Central
Microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Protein localizationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Endomembrane system
Cell junction
Cell junction, tight junction
Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions

Xu, H., Lin, X., Li, Z., He, X., Li, Y., Qiu, L., ... & He, K. (2023). VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization. Journal of Gastroenterology, 58(9), 925-944.

Yang, J. D., Chen, J. T., Liu, S. H., & Chen, R. M. (2022). Contribution of the Testosterone Androgen Receptor–PARD3B Signaling Axis to Tumorigenesis and Malignance of Glioblastoma Multiforme through Stimulating Cell Proliferation and Colony Formation. Journal of Clinical Medicine, 11(16), 4818.

Ko, K., Kitani, T., Harris, B. T., Anaizi, A. N., Solomon, D., Perry, A., ... & Ozdemirli, M. (2020). A novel PARD3B-NUTM1 fusion in an aggressive primary CNS embryonal tumor in a young adult. Acta neuropathologica communications, 8, 1-4.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-PARD3B Recombinant Antibody (8D7) (CAT#: CBMAB-A0320-LY)

Related Products

Mouse Anti-PARD3B Recombinant Antibody (E-9) (CAT#: CBMAB-P0773-YC)

Mouse Anti-PARD3B Recombinant Antibody (8D7) (CAT#: CBMAB-A0320-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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