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Mouse Anti-PARD3B Recombinant Antibody (8D7) (CBMAB-A0320-LY)

The product is antibody recognizes ALS2CR19. The antibody 8D7 immunoassay techniques such as: ELISA.
See all PARD3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
8D7
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
ALS2CR19 (NP_689739, 101 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Par-3 Family Cell Polarity Regulator Beta
Entrez Gene ID
117583
UniProt ID
Q8TEW8
Alternative Names
ALS2CR19; MGC16131; PAR3B; PAR3L; PAR3LC; PAR3beta; Par3Lb
Function
Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell cycleIEA:UniProtKB-KW
Cell divisionIEA:UniProtKB-KW
Establishment of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Establishment of centrosome localizationManual Assertion Based On ExperimentIBA:GO_Central
Establishment or maintenance of epithelial cell apical/basal polarityManual Assertion Based On ExperimentIBA:GO_Central
Microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endomembrane system
Cell junction
Cell junction, tight junction
Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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