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Mouse Anti-PCDH11X Recombinant Antibody (7B4) (CBMAB-P0961-YC)

Provided herein is a Mouse monoclonal antibody against Human Protocadherin 11 X-Linked. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PCDH11X antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7B4
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PCDH11X (NP_061850, 1228-1336 aa) partial recombinant protein with GST tag. Immunogen sequence: AQASALCYSP PLAQAAAISH SSPLPQVIAL HRSQAQSSVS LQQGWVQGAD GLCSVDQGVQ GSATSQFYTM SERLHPSDDS IKVIPLTTFT PRQQARPSRG DSPIMEEHP
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Protocadherin 11 X-Linked
Introduction
PCDH11X belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia.
Entrez Gene ID
27328
UniProt ID
Q9BZA7
Alternative Names
PCDHX; PCDH11; PPP1R119; PCDH-X
Function
Potential calcium-dependent cell-adhesion protein.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 24-812
Helical: 813-833
Cytoplasmic: 834-1347
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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