Rat Anti-PDC Recombinant Antibody (120G8) (CBMAB-P1124-YC)

Name: Rat Anti-PDC Recombinant Antibody (120G8)
SKU: CBMAB-P1124-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

120G8

Application

Specificity

Mouse

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

decarboxylase

Introduction

PDC is a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II.

Entrez Gene ID

20028

UniProt ID

Q9QW08

Alternative Names

Phosducin; 33 KDa Phototransducing Protein; PHD; Phosducin-Like Orphan Protein; G Beta Gamma Binding Protein; Protein MEKA; PhLOP; MEKA; PhLP;

Function

May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX.

Biological Process

G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
PhototransductionManual Assertion Based On ExperimentTAS:ProtInc
Regulation of G protein-coupled receptor signaling pathwayIEA:InterPro
Visual perceptionIEA:UniProtKB-KW

Cellular Location

Cytoplasm, cytosol
Nucleus
Cell projection, cilium, photoreceptor outer segment
Photoreceptor inner segment
Isoform 2
Nucleus

PTM

Light-induced changes in cyclic nucleotide levels modulate the phosphorylation of this protein by cAMP kinase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Rat Anti-PDC Recombinant Antibody (11E314) (CAT#: CBMAB-P1123-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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