Mouse Anti-PDCD2 Recombinant Antibody (DHIC2-5H10) (CBMAB-P1155-YC)

Name: Mouse Anti-PDCD2 Recombinant Antibody (DHIC2-5H10)
SKU: CBMAB-P1155-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

DHIC2-5H10

Application

FC, ICC, IF, IHC-Fr

Immunogen

Human pancreatic enriched duct cells

Specificity

Human

Antibody Isotype

IgM

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

0.05% sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Programmed Cell Death 2

Introduction

PDCD2 is a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.

Entrez Gene ID

5134

UniProt ID

Q16342

Alternative Names

Programmed Cell Death 2; Zinc Finger MYND Domain-Containing Protein 7; Zinc Finger Protein Rp-8; ZMYND7; RP8; Programmed Cell Death Protein 2;

Function

May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.

Biological Process

Activation of cysteine-type endopeptidase activity involved in apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of hematopoietic stem cell proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of hematopoietic progenitor cell differentiationManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Nucleus

PTM

Ubiquitinated by PRKN, promoting proteasomal degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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