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Mouse Anti-PDCD2 Recombinant Antibody (DHIC2-5H10) (CBMAB-P1155-YC)

Provided herein is a Mouse monoclonal antibody against Human Programmed Cell Death 2. The antibody can be used for immunoassay techniques, such as FC, ICC, IF, IHC-Fr.
See all PDCD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
DHIC2-5H10
Antibody Isotype
IgM
Application
FC, ICC, IF, IHC-Fr

Basic Information

Immunogen
Human pancreatic enriched duct cells
Specificity
Human
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
0.05% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Programmed Cell Death 2
Introduction
PDCD2 is a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
Entrez Gene ID
5134
UniProt ID
Q16342
Alternative Names
Programmed Cell Death 2; Zinc Finger MYND Domain-Containing Protein 7; Zinc Finger Protein Rp-8; ZMYND7; RP8; Programmed Cell Death Protein 2;
Function
May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of hematopoietic stem cell proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of hematopoietic progenitor cell differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
PTM
Ubiquitinated by PRKN, promoting proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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