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Mouse Anti-PDZD2 Recombinant Antibody (CBYC-P281) (CBMAB-P1387-YC)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P281
Antibody Isotype
IgG2a
Application
WB, ICC

Basic Information

Immunogen
E. coli-derived Recombinant human PDZD2, Ser2489-Ser2839
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS with trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PDZ Domain Containing 2
Introduction
PDZD2 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Entrez Gene ID
UniProt ID
Alternative Names
PDZ Domain Containing 2; Activated In Prostate Cancer Protein; PDZ Domain-Containing Protein 3; PDZK3; AIPC; Plakophilin-Related Armadillo Repeat Protein-Interactive PDZ Protein;
Biological Process
Cell adhesionIEA:UniProtKB-KW
Cellular Location
Nucleus
Cytoplasm
Endoplasmic reticulum
At cell-cell contacts in lung epithelial cells.
Processed PDZ domain-containing protein 2
Secreted
PTM
A secreted form is produced by caspase-mediated proteolytic cleavage.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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