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Mouse Anti-PEX11A Recombinant Antibody (3B1) (CBMAB-P1467-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3B1
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
peroxisomal biogenesis factor 11 alpha
Introduction
PEX11A is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance.
Entrez Gene ID
8800
UniProt ID
O75192
Alternative Names
Peroxisomal Biogenesis Factor 11 Alpha; Peroxisomal Biogenesis Factor 11A; 28 KDa Peroxisomal Integral Membrane Protein; Protein PEX11 Homolog Alpha; PEX11-ALPHA; Peroxin-11A;
Function
May be involved in peroxisomal proliferation and may regulate peroxisomes division (PubMed:9792670).
May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity).
Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).
Biological Process
Brown fat cell differentiationIEA:Ensembl
Peroxisome fissionManual Assertion Based On ExperimentIDA:UniProtKB
Peroxisome membrane biogenesisIEA:Ensembl
Peroxisome organizationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of peroxisome sizeManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Peroxisome membrane
Topology
Cytoplasmic: 1-83
Helical: 84-105
Lumenal: 106-219
Helical: 220-239
Cytoplasmic: 240-247
PTM
Seems not to be N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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