PEX11A

PEX11A is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance.

Full Name

peroxisomal biogenesis factor 11 alpha

Function

May be involved in peroxisomal proliferation and may regulate peroxisomes division (PubMed:9792670).
May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity).
Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).

Biological Process

Brown fat cell differentiationIEA:Ensembl
Peroxisome fissionManual Assertion Based On ExperimentIDA:UniProtKB
Peroxisome membrane biogenesisIEA:Ensembl
Peroxisome organizationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of peroxisome sizeManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Peroxisome membrane

Topology

Cytoplasmic: 1-83
Helical: 84-105
Lumenal: 106-219
Helical: 220-239
Cytoplasmic: 240-247

PTM

Seems not to be N-glycosylated.