PEX11A

PEX11A is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance.

Full Name

peroxisomal biogenesis factor 11 alpha

Function

May be involved in peroxisomal proliferation and may regulate peroxisomes division (PubMed:9792670).
May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity).
Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).

Biological Process

Brown fat cell differentiationIEA:Ensembl
Peroxisome fissionManual Assertion Based On ExperimentIDA:UniProtKB
Peroxisome membrane biogenesisIEA:Ensembl
Peroxisome organizationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of peroxisome sizeManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Peroxisome membrane

Topology

Cytoplasmic: 1-83
Helical: 84-105
Lumenal: 106-219
Helical: 220-239
Cytoplasmic: 240-247

PTM

Seems not to be N-glycosylated.

Anti-PEX11A antibodies

Mouse Anti-PEX11A Recombinant Antibody (3B1) (CBMAB-P1467-YC)

Datasheet

SDS

Target: PEX11A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 3B1

Application*: WB, IP, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)