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Mouse Anti-PFDN2 Recombinant Antibody (CBYC-P306) (CBMAB-P1501-YC)

Provided herein is a Mouse monoclonal antibody against Human Prefoldin Subunit 2. The antibody can be used for immunoassay techniques, such as IF, ELISA, WB.
See all PFDN2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P306
Antibody Isotype
IgG1, κ
Application
IF, ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
prefoldin subunit 2
Introduction
PFDN2 is a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
Entrez Gene ID
5202
UniProt ID
Q9UHV9
Alternative Names
PFD2
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Biological Process
Negative regulation of amyloid fibril formationManual Assertion Based On ExperimentIDA:FlyBase
Positive regulation of cytoskeleton organizationManual Assertion Based On ExperimentIDA:AgBase
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Protein stabilization3 PublicationsIC:ComplexPortal
Cellular Location
Nucleus
Cytoplasm
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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