PFDN2

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq]
Full Name
prefoldin subunit 2
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Biological Process
Negative regulation of amyloid fibril formationManual Assertion Based On ExperimentIDA:FlyBase
Positive regulation of cytoskeleton organizationManual Assertion Based On ExperimentIDA:AgBase
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Protein stabilization3 PublicationsIC:ComplexPortal
Cellular Location
Nucleus
Cytoplasm
Mitochondrion
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Anti-PFDN2 antibodies

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Mouse Anti-PFDN2 Recombinant Antibody (CBYC-P306) (CBMAB-P1501-YC)

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Target: PFDN2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYC-P306
Application*: IF, E, WB
Datasheet SDS

Mouse Anti-PFDN2 Recombinant Antibody (2C1) (CBMAB-P1500-YC)

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Target: PFDN2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C1
Application*: E, IF, WB
Datasheet SDS

Human Recombinant PFDN2 protein, His Tag (V2LY-0526-LY6119)

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Target: PFDN2
Expressed Host: E. coli
Sequence: Amino Acid: 1-154
Tag: His Tag
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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