Sign in or Register   Sign in or Register
  |  

Rabbit Anti-PFDN5 Recombinant Antibody (CBYC-P307) (CBMAB-P1504-YC)

Provided herein is a Rabbit monoclonal antibody against Human Prefoldin Subunit 5. The antibody can be used for immunoassay techniques, such as WB, IP, IHC-P.
See all PFDN5 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBYC-P307
Antibody Isotype
IgG
Application
WB, IP, IHC-P

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Prefoldin Subunit 5
Introduction
PFDN5 is a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
Entrez Gene ID
Human5204
Mouse56612
Rat300257
UniProt ID
HumanQ99471
MouseQ9WU28
RatB5DFN4
Alternative Names
Prefoldin Subunit 5; PFD5; MM1; C-Myc-Binding Protein Mm-1; C-Myc Binding Protein; Myc Modulator-1; Myc Modulator 1; Prefoldin 5; MM-1;
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Biological Process
Negative regulation of amyloid fibril formationManual Assertion Based On ExperimentIDA:FlyBase
Negative regulation of canonical Wnt signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIMP:BHF-UCL
Protein foldingManual Assertion Based On ExperimentIDA:FlyBase
Protein stabilization1 PublicationIC:ComplexPortal
Regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIBA:GO_Central
Retina development in camera-type eyeIEA:Ensembl
Cellular Location
Isoform 1
Nucleus
Isoform 2
Cytoplasm
Isoform 3
Nucleus
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-PFDN5 Recombinant Antibody (CBYC-P307)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare