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Mouse Anti-PGA5 Recombinant Antibody (13B618) (CBMAB-P1538-YC)

Provided herein is a Mouse monoclonal antibody against Human Pepsinogen 5, Group I (Pepsinogen A). The antibody can be used for immunoassay techniques, such as ELISA, IHC, WB.
See all PGA5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
13B618
Antibody Isotype
IgG1
Application
ELISA, IHC, WB

Basic Information

Immunogen
Purified recombinant fragment of human PGA5 expressed in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Pepsinogen 5, Group I (Pepsinogen A)
Introduction
PGA5 is a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
Entrez Gene ID
UniProt ID
Alternative Names
Pepsinogen 5, Group I (Pepsinogen A); Pepsinogen-5; Pepsinogen A5; EC 3.4.23.1; Pepsin A-5; Pepsin A; Pg5;
Function
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Biological Process
DigestionIEA:UniProtKB-KW
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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