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Mouse Anti-PGM3 Recombinant Antibody (1A11) (CBMAB-P1599-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Monkey
Clone
1A11
Antibody Isotype
IgG1
Application
WB, IHC-P, FC

Basic Information

Specificity
Human, Mouse, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Phosphoglucomutase 3
Introduction
PGM3 is a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy.
Entrez Gene ID
Human5238
Mouse109785
Monkey694464
UniProt ID
HumanO95394
MouseQ9CYR6
MonkeyF7G735
Alternative Names
Phosphoglucomutase 3; Acetylglucosamine Phosphomutase; EC 5.4.2.3; PGM 3; AGM1; PAGM; N-Acetylglucosamine-Phosphate Mutase 1;
Function
Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.
Biological Process
Carbohydrate metabolic processIEA:UniProtKB-KW
Glucosamine metabolic process1 PublicationNAS:UniProtKB
Glucose 1-phosphate metabolic processIEA:Ensembl
HemopoiesisManual Assertion Based On ExperimentIBA:GO_Central
Protein N-linked glycosylationManual Assertion Based On ExperimentIMP:UniProtKB
Protein O-linked glycosylationManual Assertion Based On ExperimentIMP:UniProtKB
SpermatogenesisIEA:Ensembl
UDP-N-acetylglucosamine biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytosol
Involvement in disease
Immunodeficiency 23 (IMD23):
A primary immunodeficiency syndrome characterized by recurrent respiratory and skin infections beginning in early childhood, severe atopy, increased serum IgE, and developmental delay or cognitive impairment of varying severity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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