Mouse Anti-PGM3 Recombinant Antibody (1E2-1B12) (CBMAB-P1600-YC)

Name: Mouse Anti-PGM3 Recombinant Antibody (1E2-1B12)
SKU: CBMAB-P1600-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1E2-1B12

Application

Immunogen

PGM3 (AAH01258, 1-543 aa) full length recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Phosphoglucomutase 3

Introduction

PGM3 is a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy.

Entrez Gene ID

5238

UniProt ID

O95394

Alternative Names

Phosphoglucomutase 3; Acetylglucosamine Phosphomutase; EC 5.4.2.3; PGM 3; AGM1; PAGM; N-Acetylglucosamine-Phosphate Mutase 1;

Function

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

Biological Process

Carbohydrate metabolic processIEA:UniProtKB-KW
Glucosamine metabolic process1 PublicationNAS:UniProtKB
Glucose 1-phosphate metabolic processIEA:Ensembl
HemopoiesisManual Assertion Based On ExperimentIBA:GO_Central
Protein N-linked glycosylationManual Assertion Based On ExperimentIMP:UniProtKB
Protein O-linked glycosylationManual Assertion Based On ExperimentIMP:UniProtKB
SpermatogenesisIEA:Ensembl
UDP-N-acetylglucosamine biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cytosol

Involvement in disease

Immunodeficiency 23 (IMD23):
A primary immunodeficiency syndrome characterized by recurrent respiratory and skin infections beginning in early childhood, severe atopy, increased serum IgE, and developmental delay or cognitive impairment of varying severity.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

PGM3 Matched Antibody Pair (870) (CAT#: APMAB-870LY)

PGM3 Matched Antibody Pair (871) (CAT#: APMAB-871LY)

Related Products

PGM3 Matched Antibody Pair (871) (CAT#: APMAB-871LY)

Mouse Anti-PGM3 Recombinant Antibody (CBYC-P335) (CAT#: CBMAB-P1601-YC)

Mouse Anti-PGM3 Recombinant Antibody (1A11) (CAT#: CBMAB-P1599-YC)

PGM3 Matched Antibody Pair (870) (CAT#: APMAB-870LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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