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Rabbit Anti-PHF20 Recombinant Antibody (D96F6) (CBMAB-P1661-YC)

Provided herein is a Rabbit monoclonal antibody against Human PHD Finger Protein 20. The antibody can be used for immunoassay techniques, such as WB, IP, IF.
See all PHF20 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Monkey, Cattle, Horse
Clone
D96F6
Antibody Isotype
IgG
Application
WB, IP, IF

Basic Information

Specificity
Human, Mouse, Rat, Monkey, Cattle, Horse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PHD Finger Protein 20
Introduction
PHF20 has ubiquitous expression in testis (RPKM 8.8), brain (RPKM 8.0) and 25 other tissues.
Entrez Gene ID
Human51230
Mouse228829
Rat311575
Monkey711122
Cattle529591
Horse100055019
UniProt ID
HumanQ9BVI0
MouseQ8BLG0
RatD3ZQB7
MonkeyG7N4Y3
CattleE1BMS9
HorseA0A3Q2L5P8
Alternative Names
PHD Finger Protein 20; Hepatocellular Carcinoma-Associated Antigen 58; Tudor Domain Containing 20A; Glioma-Expressed Antigen 2; Novel Zinc Finger Protein; Transcription Factor TZP; C20orf104;
Function
Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity).
As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
Biological Process
Chromatin organizationIEA:UniProtKB-KW
Histone acetylationManual Assertion Based On ExperimentIBA:GO_Central
Histone H4-K16 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Histone H4-K5 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Histone H4-K8 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of histone H3-K4 methylationManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of transcription, DNA-templated1 PublicationIC:ComplexPortal
Regulation of dosage compensation by inactivation of X chromosomeIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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