Rabbit Anti-PHF20 Recombinant Antibody (D96F6) (CBMAB-P1661-YC)

Name: Rabbit Anti-PHF20 Recombinant Antibody (D96F6)
SKU: CBMAB-P1661-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

D96F6

Application

WB, IP, IF

Specificity

Human, Mouse, Rat, Monkey, Cattle, Horse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

PHD Finger Protein 20

Introduction

PHF20 has ubiquitous expression in testis (RPKM 8.8), brain (RPKM 8.0) and 25 other tissues.

Entrez Gene ID

Human	51230
Mouse	228829
Rat	311575
Monkey	711122
Cattle	529591
Horse	100055019

UniProt ID

Human	Q9BVI0
Mouse	Q8BLG0
Rat	D3ZQB7
Monkey	G7N4Y3
Cattle	E1BMS9
Horse	A0A3Q2L5P8

Alternative Names

PHD Finger Protein 20; Hepatocellular Carcinoma-Associated Antigen 58; Tudor Domain Containing 20A; Glioma-Expressed Antigen 2; Novel Zinc Finger Protein; Transcription Factor TZP; C20orf104;

Function

Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity).
As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.

Biological Process

Chromatin organizationIEA:UniProtKB-KW
Histone acetylationManual Assertion Based On ExperimentIBA:GO_Central
Histone H4-K16 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Histone H4-K5 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Histone H4-K8 acetylationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of histone H3-K4 methylationManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of transcription, DNA-templated1 PublicationIC:ComplexPortal
Regulation of dosage compensation by inactivation of X chromosomeIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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