Mouse Anti-PHKG2 Recombinant Antibody (4B5) (CBMAB-A6644-LY)

Name: Mouse Anti-PHKG2 Recombinant Antibody (4B5)
SKU: CBMAB-A6644-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

4B5

Application

WB, ELISA

Immunogen

PHKG2 (AAH02541.1, 1 a.a. ~ 406 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, λ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Phosphorylase Kinase Catalytic Subunit Gamma 2

Entrez Gene ID

5261

UniProt ID

P15735

Alternative Names

GSD9C

Function

Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).

Biological Process

Generation of precursor metabolites and energyManual Assertion Based On ExperimentTAS:ProtInc
Glycogen biosynthetic processIEA:InterPro
Glycogen metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of glycogen catabolic processManual Assertion Based On ExperimentTAS:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

cytosol
phosphorylase kinase complex

Involvement in disease

Glycogen storage disease 9C (GSD9C):
A metabolic disorder manifesting in infancy with hepatomegaly, growth retardation, hypotonia, liver dysfunction, and elevated plasma aminotransferases and lipids. These symptoms improve with age in most cases; however, some patients may develop hepatic fibrosis or cirrhosis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

PHKG2 Matched Antibody Pair (875) (CAT#: APMAB-875LY)

Related Products

Mouse Anti-PHKG2 Recombinant Antibody (2D12) (CAT#: CBMAB-P1691-YC)

Mouse Anti-PHKG2 Recombinant Antibody (2F4) (CAT#: CBMAB-A6643-LY)

Mouse Anti-PHKG2 Recombinant Antibody (1F9) (CAT#: CBMAB-P1688-YC)

Mouse Anti-PHKG2 Recombinant Antibody (2B8) (CAT#: CBMAB-P1690-YC)

PHKG2 Matched Antibody Pair (875) (CAT#: APMAB-875LY)

Mouse Anti-PHKG2 Recombinant Antibody (2B4) (CAT#: CBMAB-P1689-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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