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Mouse Anti-PIGO Recombinant Antibody (2A4-1C3) (CBMAB-P1761-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2A4-1C3
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
PIGO (AAH01030, 1-455 aa) full length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phosphatidylinositol glycan anchor biosynthesis, class O
Introduction
PIGO is a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene.
Entrez Gene ID
84720
UniProt ID
Q8TEQ8
Alternative Names
Phosphatidylinositol Glycan Anchor Biosynthesis Class O; Phosphatidylinositol-Glycan Biosynthesis Class O Protein; GPI Ethanolamine Phosphate Transferase 3; Phosphatidylinositol Glycan, Class O; EC 2.-.-.-; HPMRS2; PIG-O;
Function
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.
Biological Process
GPI anchor biosynthetic processISS:UniProtKB
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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