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Mouse Anti-PITHD1 Recombinant Antibody (A-10) (CBMAB-P1892-YC)

Provided herein is a Mouse monoclonal antibody against Human PITH domain containing 1. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all PITHD1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
A-10
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PITH domain containing 1
Introduction
PITHD1 has ubiquitous expression in brain (RPKM 48.5), bone marrow (RPKM 31.2) and 25 other tissues.
Entrez Gene ID
Human57095
Mouse66193
Rat298557
UniProt ID
HumanQ9GZP4
MouseQ8BWR2
RatD4ABS5
Alternative Names
C1orf128; HT014; TXNL1CL
Function
Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913).
Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913).
Biological Process
Penetration of cumulus oophorusIEA:Ensembl
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of proteasomal protein catabolic processIEA:Ensembl
Spermatid developmentIEA:Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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