PITHD1

PITHD1 has ubiquitous expression in brain (RPKM 48.5), bone marrow (RPKM 31.2) and 25 other tissues.

Full Name

PITH domain containing 1

Function

Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913).
Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913).

Biological Process

Penetration of cumulus oophorusIEA:Ensembl
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of proteasomal protein catabolic processIEA:Ensembl
Spermatid developmentIEA:Ensembl

Cellular Location

Cytoplasm

Anti-PITHD1 antibodies

Mouse Anti-PITHD1 Recombinant Antibody (A-10) (CBMAB-P1892-YC)

Datasheet

SDS

Target: PITHD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: A-10

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)