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PITHD1

PITHD1 has ubiquitous expression in brain (RPKM 48.5), bone marrow (RPKM 31.2) and 25 other tissues.

Full Name

PITH domain containing 1

Function

Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913).
Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913).

Biological Process

Penetration of cumulus oophorusIEA:Ensembl
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of proteasomal protein catabolic processIEA:Ensembl
Spermatid developmentIEA:Ensembl

Cellular Location

Cytoplasm

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Anti-PITHD1 antibodies

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Mouse Anti-PITHD1 Recombinant Antibody (A-10) (CBMAB-P1892-YC)

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Target: PITHD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: A-10

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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