PITHD1
PITHD1 has ubiquitous expression in brain (RPKM 48.5), bone marrow (RPKM 31.2) and 25 other tissues.
Full Name
PITH domain containing 1
Function
Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913).
Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913).
Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913).
Biological Process
Penetration of cumulus oophorusIEA:Ensembl
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of proteasomal protein catabolic processIEA:Ensembl
Spermatid developmentIEA:Ensembl
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of megakaryocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of proteasomal protein catabolic processIEA:Ensembl
Spermatid developmentIEA:Ensembl
Cellular Location
Cytoplasm
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Anti-PITHD1 antibodies
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Target: PITHD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A-10
Application*: WB, IP, IF, E
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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