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Mouse Anti-PLA2G4F Recombinant Antibody (CBFYH-3629) (CBMAB-H4188-FY)

This product is mouse antibody that recognizes PLA2G4F. The antibody CBFYH-3629 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all PLA2G4F antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBFYH-3629
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phospholipase A2 group IVF
Introduction
Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine (By similarity).
Entrez Gene ID
Human255189
Mouse271844
Rat691907
UniProt ID
HumanQ68DD2
MouseQ50L41
RatD3Z9B7
Alternative Names
PLA2G4FZ
Function
Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators (PubMed:29158256).
Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (PubMed:29158256).
Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis (PubMed:29158256).
In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs) (PubMed:29158256).
Biological Process
Arachidonic acid secretionIEA:Ensembl
Cellular response to antibioticIEA:Ensembl
Cellular response to organic cyclic compoundIEA:Ensembl
Glycerophospholipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Phosphatidylglycerol acyl-chain remodelingTAS:Reactome
Prostaglandin biosynthetic processIEA:Ensembl
Cellular Location
Cytoplasm, cytosol
Cell membrane
Mitochondrion
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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