Mouse Anti-PLAA Recombinant Antibody (1H2) (CBMAB-P2008-YC)
Compare
Online Inquiry
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity).
May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622).
Plays a role in cerebellar Purkinje cell development (By similarity).
Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986).
Inflammatory responseIEA:Ensembl
MacroautophagyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of protein K63-linked ubiquitinationISS:UniProtKB
Nervous system developmentIEA:UniProtKB-KW
Phospholipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of dendrite extensionISS:UniProtKB
Positive regulation of neuron migrationISS:UniProtKB
Positive regulation of phospholipase A2 activityManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of synaptic vesicle recyclingISS:UniProtKB
Prostaglandin metabolic processISS:UniProtKB
Proteasome-mediated ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Ubiquitin recyclingManual Assertion Based On ExperimentIBA:GO_Central
Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathwayISS:UniProtKB
Cytoplasm
Synapse
Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
An autosomal recessive neurodevelopmental disorder characterized by progressive microcephaly, spastic quadriparesis, global developmental delay, profound intellectual disability and severely impaired or absent motor function. More variable features include seizures and optic atrophy.
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Related Products
Rabbit Anti-PLAA Recombinant Antibody (P16-D) (CAT#: CBMAB-P2012-YC)
Mouse Anti-PLAA Recombinant Antibody (2C1) (CAT#: CBMAB-P2009-YC)
Mouse Anti-PLAA Recombinant Antibody (CF344) (CAT#: CBMAB-FT161LY)
Mouse Anti-PLAA Recombinant Antibody (BSB-47) (CAT#: CBMAB-P2011-YC)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
