Mouse Anti-PLAGL1 Recombinant Antibody (CBWJZ-005) (CBMAB-Z0011-WJ)

Name: Mouse Anti-PLAGL1 Recombinant Antibody (CBWJZ-005)
SKU: CBMAB-Z0011-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBWJZ-005

Application

WB, IP, IF, IHC-P, ELISA

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

PLAG1 Like Zinc Finger 1

Introduction

This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.

Entrez Gene ID

Human	5325
Mouse	22634
Rat	25157

UniProt ID

Human	Q9UM63
Mouse	Q9JLQ4
Rat	P70616

Alternative Names

ZAC; LOT1; ZAC1

Function

Acts as a transcriptional activator (PubMed:9722527).
Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide.

Biological Process

Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Involvement in disease

Diabetes mellitus, transient neonatal, 1 (TNDM1):
An autosomal dominant form of diabetes mellitus defined by the onset of mild-to-severe hyperglycemia within the first month of life. In about half of the neonates, diabetes is transient and resolves at a median age of 3 months, whereas the rest have a permanent form of diabetes.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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