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Rat Anti-PLAUR Recombinant Antibody (CBYY-C1616) (CBMAB-C3054-YY)

This product is rat antibody that recognizes CD87. The antibody CBYY-C1616 can be used for immunoassay techniques such as: WB
See all PLAUR antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C1616
Antibody Isotype
IgG2
Application
WB

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PLAUR
Entrez Gene ID
5329
UniProt ID
Q03405
Alternative Names
CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; T-Cell Surface Glycoprotein CD8 Alpha Chain; CD8 Antigen, Alpha Polypeptide (P32); MAL; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2;
Function
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Biological Process
Blood coagulationManual Assertion Based On ExperimentTAS:ProtInc
ChemotaxisManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of apoptotic processManual Assertion Based On ExperimentIMP:CACAO
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:CACAO
Negative regulation of intrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:CACAO
Positive regulation of DNA bindingManual Assertion Based On ExperimentIDA:CACAO
Positive regulation of epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentIMP:CACAO
Positive regulation of homotypic cell-cell adhesionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIMP:CACAO
Positive regulation of release of cytochrome c from mitochondriaManual Assertion Based On ExperimentIMP:CACAO
Regulation of cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of fibrinolysis1 PublicationIC:ComplexPortal
Regulation of plasminogen activation1 PublicationIC:ComplexPortal
Regulation of proteolysis1 PublicationNAS:UniProtKB
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Urokinase plasminogen activator signaling pathway1 PublicationIC:ComplexPortal
Cellular Location
Cell membrane
Cell projection, invadopodium membrane
Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner.
Isoform 1
Cell membrane
Isoform 2
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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